One-time purchase:
$99.00 $198.00 per Fl Oz
FREE delivery Friday, May 2
Ships from: Amazon.com
Sold by: Amazon.com
FREE Returns
FREE delivery Friday, May 2
Or Prime members get FREE delivery Tuesday, April 29. Order within 4 hrs 2 mins.
In Stock
$$99.00 () Includes selected options. Includes initial monthly payment and selected options. Details
Price
Subtotal
$$99.00
Subtotal
Initial payment breakdown
Shipping cost, delivery date, and order total (including tax) shown at checkout.
Ships from
Amazon.com
Amazon.com
Ships from
Amazon.com
Sold by
Amazon.com
Amazon.com
Sold by
Amazon.com
Returns
30-day refund/replacement
30-day refund/replacement
This item can be returned in its original condition for a full refund or replacement within 30 days of receipt.
Read full return policy
Payment
Secure transaction
Your transaction is secure
We work hard to protect your security and privacy. Our payment security system encrypts your information during transmission. We don’t share your credit card details with third-party sellers, and we don’t sell your information to others. Learn more
Save 5% now and up to 10% on repeat deliveries.
  • No fees
  • Cancel anytime
 Potential yearly savings :
Learn more
FREE delivery Friday, May 2
Or Prime members get FREE delivery Tuesday, April 29. Order within 4 hrs 2 mins.
In Stock
Deliver every:
×

Added to cart

$$99.00 () Includes selected options. Includes initial monthly payment and selected options. Details
Price
Subtotal
$$99.00
Subtotal
Initial payment breakdown
Shipping cost, delivery date, and order total (including tax) shown at checkout.
Ships from
Amazon.com
Amazon.com
Ships from
Amazon.com
Sold by
Amazon.com
Amazon.com
Sold by
Amazon.com
Returns
30-day refund/replacement
30-day refund/replacement
This item can be returned in its original condition for a full refund or replacement within 30 days of receipt.
Read full return policy

iS CLINICAL Super Serum Advance+, Anti-Aging Vitamin C Face Serum, reduces scaring and fine stretch marks

4.3 out of 5 stars 332 ratings
iS CLINICAL
Premium Brand Sourced

Premium Brand Sourced

We work closely with your favorite premium beauty brands and their approved resellers to ensure the premium products sold in our stores are authentic.

Learn more
$99.00 $198.00 per Fl Oz
FREE Returns
Brief content visible, double tap to read full content.
Full content visible, double tap to read brief content.
Size: 0.5 Fl Oz (Pack of 1)
{"desktop_buybox_group_1":[{"displayPrice":"$99.00","priceAmount":99.00,"currencySymbol":"$","integerValue":"99","decimalSeparator":".","fractionalValue":"00","symbolPosition":"left","hasSpace":false,"showFractionalPartIfEmpty":true,"offerListingId":"0%2BF1TxWaYdVcKD3BDdhJhrBkVt3z%2FMUP7nn4FEM8pcKY9tCri1z4MOjILTA5nvSaLx6%2BO3wkNnIKgD2%2FZJwzQ7NwNuHp9CYqnFnvu6wWftjFfFthICGJH6w5Dp%2BFFH%2Bfrk1U2RegsOUlwmmDOUJ9Xw%3D%3D","locale":"en-US","buyingOptionType":"NEW","aapiBuyingOptionIndex":0}, {"displayPrice":"$94.05","priceAmount":94.05,"currencySymbol":"$","integerValue":"94","decimalSeparator":".","fractionalValue":"05","symbolPosition":"left","hasSpace":false,"showFractionalPartIfEmpty":true,"offerListingId":null,"locale":"en-US","buyingOptionType":"SNS","aapiBuyingOptionIndex":1}]}

Purchase options and add-ons

Skin Type Sensitive
Product Benefits Reduce signs of aging, scar tissue, stretch marks, uneven pigmentation. Stimulates collagen, promotes wound healing See more
Use for Face
Scent Aloe
Special Ingredients Vitamin C

Description

SUPER SERUM™ ADVANCE+ combines a 15% concentration of our next generation L-ascorbic acid (vitamin C) with Tripeptide-1 (Copper Tripeptide-1), for enhanced anti-aging properties.

Benefits

Reduce signs of aging, scar tissue, stretch marks, uneven pigmentation. Stimulates collagen, promotes wound healing

Suggested use

After cleaning skin, apply 3-4 drops to the palm of hand. Using fingertips, dab and smooth evenly over face and neck. Can be used morning and evening. For best results, follow complete iS CLINICAL skincare regime.
Complete the regimen
Discover product recommendations selected by Amazon Buyers
iS CLINICAL Super Serum Advance+, Anti-Aging Vitamin C...
$99.00
$539.03

Buy it with

iS CLINICAL Super Serum Advance+, Anti-Aging Vitamin C Face Serum, reduces scaring and fine stretch marks
This item: iS CLINICAL Super Serum Advance+, Anti-Aging Vitamin C Face Serum, reduces scaring and fine stretch marks
$99.00 ($198.00/Fl Oz)
Get it as soon as Wednesday, Apr 30
In Stock
Ships from and sold by LovelySkin Inc.
+
iS CLINICAL Cleansing Complex, 3in1 Gentle deep pore cleanser Face Wash and Makeup remover, Helps blemish-prone skin
$49.00 ($8.17/Fl Oz)
Get it as soon as Friday, May 2
In Stock
Ships from and sold by Amazon.com.
+
iS CLINICAL Active Serum - Visibly evens skin tone, Excellent for blemish prone skin, Anti-Aging Face Serum
$92.00 ($184.00/Fl Oz)
Get it as soon as Wednesday, Apr 30
In Stock
Ships from and sold by LovelySkin Inc.
Total price: $00
To see our price, add these items to your cart.
Details
Added to Cart
These items are shipped from and sold by different sellers.
Show details Hide details
Choose items to buy together.

From the brand

From the manufacturer

recommended by skincare professionals globally
age-defying super antioxident reduce fine lines improve stretch marks brighten uneven skin tone
key ingredients vit c glow centella asiatica healing properties diminish aging mushroom brighten
visible improvements in uneven skin tone and scarring
reduce the appearance of fine lines wrinkles safely brighten diminsh unvevn skin tone suppr
The video showcases the product in use.The video guides you through product setup.The video compares multiple products.The video shows the product being unpacked.

Product details

  • Is Discontinued By Manufacturer ‏ : ‎ No
  • Product Dimensions ‏ : ‎ 2.68 x 1.38 x 4 inches; 2.72 ounces
  • Item model number ‏ : ‎ 1008
  • UPC ‏ : ‎ 012354114401 179654080260 885407387905 817244010104 885734037382 123541144016
  • Manufacturer ‏ : ‎ iS CLINICAL
  • ASIN ‏ : ‎ B0027583BO
  • Country of Origin ‏ : ‎ USA
  • Customer Reviews:
    4.3 out of 5 stars 332 ratings

Customer reviews

4.3 out of 5 stars
332 global ratings

Review this product

Share your thoughts with other customers
Write a customer review

Customers say

Customers find the serum effective at improving skin tone, with one noting it softens fine lines around the eyes and forehead. The product receives positive feedback for its quality and effectiveness, with one customer reporting decreased inflammation after several months of daily use. While some customers find it worth the price, others disagree, and opinions are mixed about its texture, with some experiencing tingling while others report no tingling sensation. The serum's thickness receives negative feedback, with customers finding it thicker than expected.

AI-generated from the text of customer reviews

Select to learn more

26 customers mention "Skin tone"23 positive3 negative

Customers report positive effects on their skin tone, noting that the serum brightens and improves complexion, with one customer mentioning it softens fine lines around the eyes and forehead.

"Several drops put on clean skin at night leaves you looking fresh in the morning. Skin is dewier. Lines soften out...." Read more

"...Now, my skin is much more even toned, brighter, and more youthful. I don’t see a reason to go back to SkinC." Read more

"This is a wonderful product and keeps your complexion blemish free and wrinkles under control...." Read more

"...Either way, it has brightened my skin and faded red marks relatively quickly (within a couple weeks). Just please, beware of your supplier...." Read more

13 customers mention "Quality"11 positive2 negative

Customers find the serum to be of good quality, with one customer specifically noting the high-quality ingredients.

"This is a wonderful product and keeps your complexion blemish free and wrinkles under control...." Read more

"...but seriously, the ingredients are quality, moisturizing, and brightening if your skin can handle vit c.. at first, my skin needed time to adjust to..." Read more

"Better products that I've ever bought" Read more

"...Skin looks radiant. Overall a good product." Read more

5 customers mention "Effectiveness"5 positive0 negative

Customers find the serum effective, with individual reviews mentioning it works well with melasma inhibitors, helps with dark spots, and reduces inflammation with daily use.

"I love how it makes my face glow and it helps with my dark spots." Read more

"Be kind to your skin, it works! It's worth the price, lasts long time and visible results. Used for years...." Read more

"Works well with melasma inhibitors or skin lighteners. Good for mature skin...." Read more

"...circles, hyperpigmentation from acne scarring and decreased inflammation in a few months of daily (morning) use. Works best when used with sunscreen." Read more

4 customers mention "Ease of use"4 positive0 negative

Customers find the serum easy to use, with individual reviews noting its effectiveness in smoothing out fine lines and improving skin texture.

"...Skin is dewier. Lines soften out. This is my new favorite product. Of all the products I've tried, this actually works!..." Read more

"...Lines seem to have almost vanished (I'm 57). I have sensetive skin and this was not harsh, nor did it break out my skin...." Read more

"...My face is glowing and have completely evened out. I had some faint sun spots that are all but gone...." Read more

"I love this product! It quenches my skin and smooths out fine lines and evens out my coloring!" Read more

20 customers mention "Value for money"7 positive13 negative

Customers have mixed opinions about the serum's value for money, with some finding it worth the price while others consider it pricey.

"...Of all the products I've tried, this actually works! It is expensive, but worth it." Read more

"Worth every penny. Its for skin discoloration, ok let me be honest i have been cutting chemicals out little by little...." Read more

"...pictures before I return as this is not the real product which is not cheap! Would LOVE for the seller to contact me." Read more

"...It's very expensive, but worth it." Read more

12 customers mention "Skin texture"8 positive4 negative

Customers have mixed experiences with the serum's texture, with some noting a tingling sensation while others report no tingling at all.

"...Skin is dewier. Lines soften out. This is my new favorite product. Of all the products I've tried, this actually works!..." Read more

"...It tingles a little when you put it on but it does not really bother me. I will definitely continue to use this stuff, its awesome." Read more

"...but seriously, the ingredients are quality, moisturizing, and brightening if your skin can handle vit c.. at first, my skin needed time to adjust to..." Read more

"...recommend this to anyone with sensetive skin who wants their skin to feel soft and look radiant. I get SO many compliments on my skin...." Read more

6 customers mention "Thickness"0 positive6 negative

Customers have mixed opinions about the serum's thickness, with some finding it a bit thicker while others note it is lighter than normal.

"...It should be yellow and a bit thicker and is clear like water...." Read more

"...to when I’ve purchased directly from my aesthetician, this serum is thinner, lighter, and mysteriously effervescent...." Read more

"...The solution is thicker on the official’s one compared to Amazon’s. Feels different too, returned." Read more

"...This serum seemed super watery and lighter than normal. I have a feeling they diluted it and not sure why it was only half full." Read more

Recommend buying directly from licensed aesthetician or iS Clinical!
1 out of 5 stars
Recommend buying directly from licensed aesthetician or iS Clinical!
I’m returning this product because it appears to be diluted. Compared to when I’ve purchased directly from my aesthetician, this serum is thinner, lighter, and mysteriously effervescent. My best guess is that it’s diluted somehow, especially when you compare them side by side (the smaller bottle on the left was purchased from Amazon, the larger bottle on the right was purchased directly from my aesthetician).
Hide
Thank you for your feedback
Sorry, there was an error
Sorry we couldn't load the review

Top reviews from the United States

  • LTM
    5.0 out of 5 stars It actuallyworks.
    Reviewed in the United States on December 29, 2022
    Size: 1 Fl Oz (Pack of 1)Verified Purchase
    Several drops put on clean skin at night leaves you looking fresh in the morning. Skin is dewier. Lines soften out. This is my new favorite product.
    Of all the products I've tried, this actually works! It is expensive, but worth it.
    17 people found this helpful
    Helpful
     Report
  • Gab
    5.0 out of 5 stars Quality product
    Reviewed in the United States on April 15, 2025
    Size: 1 Fl Oz (Pack of 1)Verified Purchase
    I recommend this product
    Helpful
     Report
  • Beauty Customer
    5.0 out of 5 stars Super serum indeed
    Reviewed in the United States on October 8, 2022
    Size: 1 Fl Oz (Pack of 1)Verified Purchase
    This is it. A holy grail Vitamin C serum on the level of SkinCeuticals CE Ferulic. In fact, I find this serum absorbs much more quickly and doesn’t leave my face shiny as I start my day (my one grievance with the SkinC). When I first started using it every morning, my skin did start to flake slightly. But I pushed through, and the flaking quickly alleviated. Now, my skin is much more even toned, brighter, and more youthful. I don’t see a reason to go back to SkinC.
    23 people found this helpful
    Helpful
     Report
  • GEO
    4.0 out of 5 stars Super Serum
    Reviewed in the United States on June 6, 2011
    Verified Purchase
    Too soon to tell results; the serum claims to help skin both firmness and color fading (scars); imagine it will take time.
    3 people found this helpful
    Helpful
     Report
  • Fakrwee
    5.0 out of 5 stars WONDERFUL PRODUCT FOR 50+ SKIN
    Reviewed in the United States on March 1, 2016
    Verified Purchase
    This is a wonderful product and keeps your complexion blemish free and wrinkles under control. Others have written that this is a fraud because of the color of the product, but that is not true. The fluid in the regular IS Clinical in a blue bottle is clear, but the fluid in the Advance Serum+ in an amber bottle is amber (light yellow). This is a review for the Advance Serum+. I first became familiar with the blue bottle formula used at a day spa and purchased it from them. Subsequently I moved across the country and searched Amazon for the product. I decided to try the advanced formula and found a remarkable difference. I only use it in the morning so it lasts me 9-10 months. It's a great product!!
    19 people found this helpful
    Helpful
     Report
  • KL
    1.0 out of 5 stars I am worried this not the real product
    Reviewed in the United States on January 9, 2025
    Size: 0.5 Fl Oz (Pack of 1)Verified Purchase
    First of all I have LOVE this product when I get from my dermatologist. My Dermatolgist rain out so thought I would try Amazon! I’m returning this product because it appears to be diluted. It should be yellow and a bit thicker and is clear like water. This can’t be the product (unless they completely changed the product and smell) and I am deeply concerned on what I just put on my face! I am taking pictures before I return as this is not the real product which is not cheap! Would LOVE for the seller to contact me.
    Helpful
     Report
  • alegna222
    5.0 out of 5 stars Same results as Skinceuticals
    Reviewed in the United States on May 31, 2024
    Size: 0.5 Fl Oz (Pack of 1)Verified Purchase
    I was using Skinceuticals C E Ferulic Acid serum for a couple years before this and every time it ran out I'd try to find other options to save some money. My esthetician recommended this and I've see no change in my skin so I see no reason to spend an extra $80 on Skinceuticals.
    4 people found this helpful
    Helpful
     Report
  • Anthony J. Lowry
    5.0 out of 5 stars Be aware of the supplier you buy from!!
    Reviewed in the United States on February 1, 2016
    Verified Purchase
    This super serum is the best of the IS clinical line, imo. it's the only one without alcohol, which is good "because alcohol dries your face out and makes you look older" ;)

    but seriously, the ingredients are quality, moisturizing, and brightening if your skin can handle vit c.. at first, my skin needed time to adjust to it (a couple of days).

    Either way, it has brightened my skin and faded red marks relatively quickly (within a couple weeks). Just please, beware of your supplier. I would avoid products sold by PSYDUCKONLINE. I've bought from this distributor a few times and I do not trust them. They watered down the samples I bought from them a couple years back.
    75 people found this helpful
    Helpful
     Report

Top reviews from other countries

Translate all reviews to English
  • Mit
    1.0 out of 5 stars Producto abierto y usado y no me han devuelto mi dinero.
    Reviewed in Mexico on August 30, 2019
    Size: 1 Fl Oz (Pack of 1)Verified Purchase
    El producto venía abierto y usado, solocite la devolución el mismo día que lo recibí y regresé el suero y aún no me han hecho la devolución
    Report
  • I am very disappointed, no precise information, they delay the parcel without any explanation, I have been waiting for it for almost 2 weeks, and then they add another five days, is anyone even going to solve this problem
    1.0 out of 5 stars improve service
    Reviewed in Saudi Arabia on August 10, 2024
    Size: 1 Fl Oz (Pack of 1)Verified Purchase
    So far so good
    Report
  • Amazon Customer
    5.0 out of 5 stars Great clinical grade product
    Reviewed in the United Kingdom on May 25, 2021
    Size: 0.5 Fl Oz (Pack of 1)Verified Purchase
    Used it a week so far and my skin feels firm and less wrinkly, definitely a brighter complexion and my acne scars are starting to fade. It hydrates without making your face look greasy or oily. Will defo buy again. Great price compared to other clinical based products out there.
    Report
  • Amazon Kunde
    5.0 out of 5 stars Super Produkt
    Reviewed in Germany on October 7, 2022
    Size: 0.5 Fl Oz (Pack of 1)Verified Purchase
    Meine Kosmetiker hat mir die Produkte von iS Clinical empfohlen und ich bin mega happy. Benutze 3 Produkte aus der Serie und meine Haut sieht beruhigter aus und die Poren feiner. Keine Reaktion oder ähnliches. Meine haut musste sich auch nicht dran gewöhnen. Habe das Serum schon einige male verschenkt. Alle sind zufrieden und glücklich
    Report
  • Irina E.
    4.0 out of 5 stars Super, würde ich jederzeit nochmals kaufen
    Reviewed in Germany on January 12, 2019
    Size: 0.5 Fl Oz (Pack of 1)Verified Purchase
    Ich habe nach einer hautanalyse und Empfehlung eines kosmetikstudios dieses Produkt besorgt. Es ist unglaublich, wie wirkungsvoll das serum ist. Ich bin begeistert, wie strahlend meine Haut nach drei Wochen ist.
    Report