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Microbiome Labs MegaSporeBiotic Probiotics for Women & Men - Spore Based Probiotics for Digestive Health - Shelf Stable & Travel-Friendly (60 Capsules)

4.6 out of 5 stars 3,029 ratings
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Purchase options and add-ons

Brand Microbiome Labs
Flavor Unflavoured
Primary Supplement Type Spore Based Probiotic
Unit Count 60 Count
Item Form Capsule
Item Weight 0.05 Kilograms
Item dimensions L x W x H 1.75 x 1.75 x 4 inches
Special Ingredients 5 Bacillus Spores
Diet Type Gluten Free
Product Benefits Gut Microbiome Support

About this item

  • 100% Spore-Based Probiotics - Our probiotic nutritional supplements can help support normal gut health by effectively reconditioning the gut. The spore based probiotic formula promotes microbial diversity and the maintenance of key health-promoting, commensal gut flora.*
  • DNA-Verified Bacillus Strains - Includes bacillus subtilis, bacillus indicus, bacillus subtilis, bacillus licheniformis, bacillus clausii and bacillus coagulans probiotics for digestive health. We suggest starting with 1/2 a capsule or 1 full capsule with food and slowly increasing to 2 probiotic capsules per day, or as directed by your healthcare practitioner.
  • Survives Digestion - The bi-phasic life cycle of the bacillus probiotics allows them to remain dormant in harsh environments until they reach more favorable environments like the human gastrointestinal tract. Once inside the large intestine, these dormant spores can change into their active, vegetative forms and begin colonizing to support daily gut health for women and men.*
  • No Refrigeration Required - Spore-based digestive probiotic formulas can withstand a wide range of temperatures and are a travel-friendly option for the whole family. Probiotics for women, men, teens, and children age 5 and up.
  • Science You Can Trust - We created the category of spore-based probiotics, and are backed by the biotech world leader Novozymes OneHealth. When creating our men's and women's probiotics for gut health, we control every step of our innovation and formulation process, from strain discovery to final product.

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Product Description

probiotics for women probiotic probiotics probiotics for men probiotics for digestive health
soil based probiotic organic probiotic probiotic supplements spore based probiotic
bacillus subtilis probiotic gut health digestive supplements
probiotics prebiotic probiotic with prebiotic
TGR gut support gut health supplements

Combine with Customer Favorite Microbiome Labs Products

MegaSporeBiotic

MegaSporeBiotic Gummies

MegaPre

MegaMucosa

Total Gut Restoration

FidoSpore

Customer Reviews
4.6 out of 5 stars 3,029
4.6 out of 5 stars 3,029
4.7 out of 5 stars 56
4.2 out of 5 stars 194
4.6 out of 5 stars 3
4.3 out of 5 stars 74
Price
$64.99 $26.10 $71.39 $71.39 $53.95
Product
Spore-Based Probiotic Spore-Based Probiotic Prebiotic Gut Mucosa Support 4-Piece Kit Dog + Cat Probiotic
Form
Capsules Gummies Powder Powder Capsules + Powder Capsules
Benefits
Gut, Immune, Antioxidant Gut, Immune, Antioxidant Enhances probiotic benefits* Supports healthy gut lining* Comprehensive gut support* Digestive support*
Key Ingredients
5 Bacillus Spores 4 Bacillus Spores Clinically tested prebiotics Aminos, Immunoglobulins Probiotic, MegaPre, MegaMucosa Probiotic, Beef Liver
Practitioner Trusted

Product details

  • Is Discontinued By Manufacturer ‏ : ‎ No
  • Product Dimensions ‏ : ‎ 1.75 x 1.75 x 4 inches; 1.76 ounces
  • Date First Available ‏ : ‎ June 25, 2019
  • Manufacturer ‏ : ‎ Microbiome Labs
  • ASIN ‏ : ‎ B07TJ4TH8Q
  • Customer Reviews:
    4.6 out of 5 stars 3,029 ratings

Important information

Safety Information

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Please consult your healthcare professional prior to use, especially if you have or suspect a medical condition, have any allergies, are taking any prescriptions, or are pregnant or lactating.

Ingredients

Bacillus indicus (HU36), Bacillus subtilis (HU58), Bacillus coagulans (SC-208), Bacillus licheniformis (SL-307), Bacillus clausii (SC-109), Cellulose, Vegetable Capsule.

Directions

Suggested Use: Start with 1/2 capsule or 1 full capsule with food and slowly increase to 2 capsules per day using the following protocol.

Legal Disclaimer

Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.

Customer reviews

4.6 out of 5 stars
3,029 global ratings

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Customers say

Customers report that the probiotic supplement works well for gut health, helping with digestive issues and chronic constipation. The product receives positive feedback for its quality, with one customer noting it strengthens gut microbiome, and customers find it tastes great. While some customers consider it good value, others say it's not worth the price. Several customers experienced stomach pain, including nausea and severe cramping.

AI-generated from the text of customer reviews

80 customers mention "Works well"80 positive0 negative

Customers find that the probiotic supplement works well for good gut health.

"...I have been taking them for over a year and they never fail. Being able to order them on Amazon makes it easy. The price is good too." Read more

"...Spore probiotics, being hardier and able to survive the voyage through your gut, require a more watchful approach...." Read more

"great product" Read more

"Good quality. Work well." Read more

77 customers mention "Gut health"65 positive12 negative

Customers report positive effects on gut health, noting improvements in digestive issues and chronic constipation.

"...market- it's spore-based, meaning it will get past your gut and into your colon! Yay! I notice a huge difference between this probiotic and others...." Read more

"...suggested this particular product to help me attain and maintain a healthy gut." Read more

"...Spore probiotics, being hardier and able to survive the voyage through your gut, require a more watchful approach...." Read more

"My toddler loves these and they really helped keep his belly happy when on antibiotics!" Read more

69 customers mention "Probiotic quality"69 positive0 negative

Customers praise this probiotic supplement for its effectiveness in strengthening gut microbiome, with one customer noting how it replaces unhealthy bacteria with beneficial ones.

"The best probiotic on the market- it's spore-based, meaning it will get past your gut and into your colon! Yay!..." Read more

"Fantastic probiotic recomended by my clinical nutritious. I have been taking them for over a year and they never fail...." Read more

"The best probiotic I've ever used. My doctor suggested this particular product to help me attain and maintain a healthy gut." Read more

"great product if you travel allot. Using a refrigerated pro-biotic is always best." Read more

8 customers mention "Taste"6 positive2 negative

Customers like the taste of these probiotics.

"...There isn’t any weird taste to these so don’t worry about that. Read the bottle as you need to increase the amount per week." Read more

"My homeopathic dr recommended this brand for my daughter, she really likes the taste and hopefully it’s helping!" Read more

"...The worst part was developing food intolerances I've never had before which probiotics are supposed to help with, not create...." Read more

"Love these probiotics. Most effective strains and easy to swallow, no taste." Read more

51 customers mention "Value for money"17 positive34 negative

Customers have mixed opinions about the probiotic supplement's value for money, with some finding it good value while others say it's not worth the price.

"...My kids all take them daily! It is a bit more expensive, but you get what you pay for with probotics!..." Read more

"...Being able to order them on Amazon makes it easy. The price is good too." Read more

"Good probiotic! A little pricey but very good!" Read more

"...and the exorbitant cost! They quote the price per capsule (unit) but this is meaningless because..." Read more

30 customers mention "Stomach pain"0 positive30 negative

Customers report experiencing stomach issues with this probiotic supplement, including nausea, severe cramping, and constipation.

"...Then I took one more and same symptoms of die off that felt like food poisoning, so I stopped completely...." Read more

"...but this time when I took it I had horrible days with stomach cramps and diaherra ...." Read more

"...I took one full pill with dinner and the next morning I felt nauseous and low energy. I went to the use the bathroom FIVE TIMES!!!..." Read more

"...After a week, the detrimental side effects were so bad that I had to discontinue use...." Read more

Amazing and powerful probiotic 👍
5 out of 5 stars
Amazing and powerful probiotic 👍
I discovered this type of probiotic while reading Dr. Izabella Wentz's book.Although I had tried many probiotics before, I had never heard of spore-based probiotics.I started with half a capsule on the first and second days, then increased to one capsule on the third and fourth days, gradually building up until I reached two capsules—one in the morning and one in the evening.I've purchased it multiple times, but to be honest, I live a very healthy lifestyle. I don't consume gluten, sweets, or any processed foods at all.Because of this, I didn’t experience any unusual reactions in my gut initially, as I don’t suffer from bacterial overgrowth. I really liked the product, and now I’ve started giving it to my husband using the same gradual approach, and he says it has helped him.I am not a doctor; I’m a reader with a strong passion for functional medicine. I want to mention that for those who struggle to tolerate probiotics, they might want to look into postbiotics or Tributyrin (a component used in some postbiotics). I believe this suits most people, especially those with ulcerative colitis, Crohn's, or intestinal inflammation.
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Top reviews from the United States

  • Reviewed in the United States on January 29, 2025
    Size: 180 Count (Pack of 1)Style: CapsulesVerified Purchase
    The best probiotic on the market- it's spore-based, meaning it will get past your gut and into your colon! Yay! I notice a huge difference between this probiotic and others. My kids all take them daily! It is a bit more expensive, but you get what you pay for with probotics! I have major stomach issues and this is a must daily for me! If your diet is horrible follow the directions and start slow.
    18 people found this helpful
    Report
  • Reviewed in the United States on March 29, 2025
    Size: 180 Count (Pack of 1)Style: CapsulesVerified Purchase
    Fantastic probiotic recomended by my clinical nutritious. I have been taking them for over a year and they never fail. Being able to order them on Amazon makes it easy. The price is good too.
  • Reviewed in the United States on March 28, 2025
    Size: 60 Count (Pack of 1)Style: CapsulesVerified Purchase
    The best probiotic I've ever used. My doctor suggested this particular product to help me attain and maintain a healthy gut.
  • Reviewed in the United States on January 28, 2025
    Size: 180 Count (Pack of 1)Style: CapsulesVerified Purchase
    I discovered this type of probiotic while reading Dr. Izabella Wentz's book.
    Although I had tried many probiotics before, I had never heard of spore-based probiotics.
    I started with half a capsule on the first and second days, then increased to one capsule on the third and fourth days, gradually building up until I reached two capsules—one in the morning and one in the evening.
    I've purchased it multiple times, but to be honest, I live a very healthy lifestyle. I don't consume gluten, sweets, or any processed foods at all.
    Because of this, I didn’t experience any unusual reactions in my gut initially, as I don’t suffer from bacterial overgrowth. I really liked the product, and now I’ve started giving it to my husband using the same gradual approach, and he says it has helped him.
    I am not a doctor; I’m a reader with a strong passion for functional medicine. I want to mention that for those who struggle to tolerate probiotics, they might want to look into postbiotics or Tributyrin (a component used in some postbiotics). I believe this suits most people, especially those with ulcerative colitis, Crohn's, or intestinal inflammation.
    Customer image
    5.0 out of 5 stars
    Amazing and powerful probiotic 👍

    Reviewed in the United States on January 28, 2025
    I discovered this type of probiotic while reading Dr. Izabella Wentz's book.
    Although I had tried many probiotics before, I had never heard of spore-based probiotics.
    I started with half a capsule on the first and second days, then increased to one capsule on the third and fourth days, gradually building up until I reached two capsules—one in the morning and one in the evening.
    I've purchased it multiple times, but to be honest, I live a very healthy lifestyle. I don't consume gluten, sweets, or any processed foods at all.
    Because of this, I didn’t experience any unusual reactions in my gut initially, as I don’t suffer from bacterial overgrowth. I really liked the product, and now I’ve started giving it to my husband using the same gradual approach, and he says it has helped him.
    I am not a doctor; I’m a reader with a strong passion for functional medicine. I want to mention that for those who struggle to tolerate probiotics, they might want to look into postbiotics or Tributyrin (a component used in some postbiotics). I believe this suits most people, especially those with ulcerative colitis, Crohn's, or intestinal inflammation.
    Images in this review
    Customer image
    28 people found this helpful
    Report
  • Reviewed in the United States on December 16, 2023
    Size: 60 Count (Pack of 1)Style: CapsulesVerified Purchase
    I will be updating this every few months.

    Both my spouse and I have begun taking a Spore Probiotic.
    I have two brands we are using. I am on the Youtheory.
    My spouse is on Microbiome Labs MegaSporeBiotic. We are both
    within normal weight range with 10 lbs to lose each, to put us at
    Ideal weight within that same normal BMI.

    1: One of us is SIBO gut challenged. I had been on PPI on and off,
    and finally became compliant, to the point that small intestine bacterial
    overgrowth occurred. What my doctor viewed as successful dosing, in
    turn served me up a horrid gut imbalance. That, in under a year of
    Compliance, so watch out if you are on PPI, the signs are bloating and
    often a flip flop between constipation and diarrhea. It only seems mild
    until it crosses the line to intolerable.

    2: The other of us is pre-diabetic, cholesterol, early kidney challenged.
    There are studies that note that B Subtilis may influence glucose transporters
    to benefit those who have challenges, as well as other spores which
    Influence cholesterol positively.

    Spore probiotic have a long lifecycle and slowly colonize the GI tract.
    They have a span of 3-4 weeks, compared to the 4-7 days of traditional
    probiotics. A traditional probiotic has a low survival rate in arriving,
    thus, more billions upon billions are required in dosage. Thus the smaller
    dosage of Spore Probiotics which are 3 billion per capsule, is actually
    superior to the many more billions of the traditional probiotics. That
    said, smaller doses over time are the approach I am taking.

    There are so many studies and for a great reason, all the evidence is
    pointing to Spore Probiotics being beneficial.

    Spore probiotics, being hardier and able to survive the voyage through your gut,
    require a more watchful approach.

    As many manufactures of Spore Probiotics state, start out slow and work
    your way up to a larger dose. This makes perfect sense. That of course
    does not factor in age related issues, health challenges, SIBO, IBS etc.

    The last thing you want is to experience something (nausea, diarrhea,
    fatigue, un-wellness) if indeed a different approach could have been taken.

    So while die-off symptoms can be severe when they hit, working up
    slowly in dose can negate much of that hardship!

    That said, I forgot that rule of thumb and did the first week starting out
    a touch quicker than I should have, before switching over to an every other
    day regimen halfway through the week. What hit was a touch of not
    feeling quite well, and taking a break from activities to recover.

    The other person I simply started at 1 capsule, every third day, as I did
    not want that person to experience any challenge. That person in
    turn, did well with the first week.

    Thus I kept to an every third day schedule for the first two weeks,
    prior to graduating to every other day for the next two weeks.

    At this dosage, the first month will not present the outcome of
    regular use, but it will serve to ease us into this new probiotic without
    much of the side effects of die off.

    I will update this in a couple of months.
    301 people found this helpful
    Report
  • Reviewed in the United States on March 16, 2025
    Size: 30 Count (Pack of 1)Style: GummiesVerified Purchase
    great product if you travel allot. Using a refrigerated pro-biotic is always best.
    One person found this helpful
    Report
  • Reviewed in the United States on March 30, 2025
    Size: 60 Count (Pack of 1)Style: CapsulesVerified Purchase
    Good probiotic! A little pricey but very good!
  • Reviewed in the United States on March 27, 2025
    Size: 180 Count (Pack of 1)Style: CapsulesVerified Purchase
    These spore Biotics are one of the best I’ve found.
    One person found this helpful
    Report

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