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Neocutis Bio Serum Firm - Hydrating and Anti-Aging Serum - 30ml
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Return this item for free
We offer easy, convenient returns with at least one free return option: no shipping charges. All returns must comply with our returns policy.
Learn more about free returns.- Go to your orders and start the return
- Select your preferred free shipping option
- Drop off and leave!
Skin Type | All |
Product Benefits | Supports collagen, elastin, and hyaluronic acid production that helps brighten skin tone and boost hydration. See more |
Use for | Face |
Scent | Fragrance Free |
Special Ingredients | Arginine, Proprietary Peptides, Sodium Hyaluronate, Glutamine |
Description
Benefits
Suggested use
Frequently purchased items with fast delivery
From the brand

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Over 15 years ago, NEOCUTIS was founded on the basis of extensive wound-healing research. Their wound healing technology was found to help heal skin making it appear healthier. NEOCUTIS scientists began to explore how to apply the same principles to improve the appearance of aging skin. And they accomplished just that!
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Rooted in Research
NEOCUTIS’s ongoing, cutting-edge research and meticulous craftsmanship delivers targeted skincare to help nourish and rejuvenate skin.
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Shop Best Sellers
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Award-Winning Moisturizer
NEOCUTIS’s Lumiere Firm Riche was the winner of the Marie Claire: Favorite for Mature Skin Award (2023)!
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Hand-Crafted Formulations
This collection of anti-aging products is proven to rejuvenate and help improve the appearance of skin.
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Shop NEOCUTIS Skincare
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Award-Winning Cleanser
NEOCUTIS’s NeoCleanse Gentle Cleanser was the winner of InStyle’s Best Cleanser for Dry and Sensitive Skin Beauty Award (2023)!
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Bio Cream Firm
Formulated with proprietary peptides, this face cream decreases signs of aging including uneven tone, wrinkles, and sagginess.
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Lumière Firm Riche
This award-winning eye cream targets the delicate eye area to reduce the appearance of crow’s feet, puffiness, and under-eye darkness.
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Bio Serum Firm
This luxury serum minimizes the appearance of wrinkles, refines texture, brightens skin tone, and boosts elasticity and hydration.
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What skin types can use NEOCUTIS?
NEOCUTIS products are formulated for all skin types including normal, dry, oily, and combination skin. We recommend consulting your provider to learn which NEOCUTIS products are best for your skin type.
Do NEOCUTIS products require a prescription?
No.
Is NEOCUTIS safe for sensitive skin?
NEOCUTIS products are formulated for skin tolerability. The skin tolerability of these products was evaluated during standard dermatological studies for cosmetic products. Speak with your healthcare provider regarding what products are safe for your skin.
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What is Bio Cream Firm?
Based on Bio Cream, the original anti-aging, growth-factor formulation, this new combination treatment also contains our proprietary peptides.
What is Bio Serum Firm?
A: Based on Bio Cream, the original anti-aging, growth-factor formulation, this new combination formulation also contains our proprietary peptides.
What is Bio Gel Firm?
A: Bio Gel Firm is an evolution of Bio Gel, our anti-aging, growth-factor formulation, now paired with proprietary peptides to additionally support collagen and elastin.
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How is Bio Cream Firm different from Bio Cream?
New Bio Cream Firm integrates growth factors with proprietary peptides in one effective formulation. Bio Cream Firm also contains argan oil.
What results have been seen with Bio Cream Firm?
In a consumer perception study, users expressed high satisfaction with results after both 14 and 30 days of twice-daily use.
Are NEOCUTIS products ethical and cruelty-free?
Yes. NEOCUTIS does not test our products on animals. NEOCUTIS skincare is dermatologist-tested, non-comedogenic, and free of color additives or fragrance.
From the manufacturer




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Neo Cleanse Gentle Skin Cleanser
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Bio Serum Firm
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Lumière Firm Illuminating & Tightening Eye Cream
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Bio Cream Firm
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Customer Reviews |
4.4 out of 5 stars 93
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4.6 out of 5 stars 119
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4.5 out of 5 stars 620
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4.5 out of 5 stars 122
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Price | $40.00$40.00 | $101.60$101.60 | $91.20$91.20 | $150.40$150.40 |
Step | 1. Cleanser | 2. Serum | 3. Eye Cream | 4. Moisturizer |
How to Use | Dispense a small amount into the hand and mix with some water. Massage over wet face, neck and décolletage in a circular motion. Rinse thoroughly with warm water and pat dry. | Apply in the morning and/or evening to the face, neck, and décolleté, or as directed by your skincare professional. | Apply in the morning and evening to the skin surrounding the eye, or as directed by your skincare professional. | Apply in the morning and/or evening to the face, neck and décolleté, or as directed by your skincare professional. |
Target Area | Face and Décolletage | Face and Décolletage | Eye Area | Face and Décolletage |
Key Benefits | Gently washes away makeup and surface impurities while hydrating. | Minimizes the appearance of fine lines and wrinkles, refines texture, brightens skin tone, improves firmness and elasticity, and boosts hydration. | Reduces the appearance of fine lines and wrinkles, crow’s feet, puffiness and under-eye darkness. | Addresses signs of aging including uneven tone and texture, wrinkles, and sagginess. |
Product details
- Product Dimensions : 4.5 x 1.4 x 1.4 inches; 2.08 ounces
- UPC : 186295000984
- Manufacturer : AmazonUs/F5NME
- ASIN : B081KMCB8X
- Country of Origin : USA
- Best Sellers Rank: #56,003 in Beauty & Personal Care (See Top 100 in Beauty & Personal Care)
- #1,270 in Facial Serums
- Customer Reviews:
Videos
Videos for this product
10:01
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Honest Review of Neocutis Bio Serum Firm
JaggedHaloLLC - Kim Herring
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0:08
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Neocutis Bio Serum Firm - Hydrating and Anti-Aging Serum
NeoCutis
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0:44
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Honest review of Neocutis Bio Serum Firm - Hydrating Serum
Ladonna Jack
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0:17
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Neocutis Bio Serum Firm - Hydrating and Anti-Aging
V&A Marketing
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0:54
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Neocutis Bio Serum Firm - Hydrating and Anti-Aging
⭐️⭐️⭐️⭐️⭐️ Review
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Skincare Essential- La Roche-Posay Hyalu B5 Riche Cream
TommyG's Reviews
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Customer reviews
Customer Reviews, including Product Star Ratings help customers to learn more about the product and decide whether it is the right product for them.
To calculate the overall star rating and percentage breakdown by star, we don’t use a simple average. Instead, our system considers things like how recent a review is and if the reviewer bought the item on Amazon. It also analyzed reviews to verify trustworthiness.
Learn more how customers reviews work on AmazonCustomers say
Customers find the serum effective and of good quality, with one describing it as the best on the market. Moreover, they report positive results for skin tone, with one customer noting their skin looks and feels better, while another mentions it's beneficial for aging skin. Additionally, the texture receives positive feedback, with one customer describing it as soft and silky to apply. However, customers disagree on whether the product is worth its price.
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Customers find the serum to be of good quality, with one customer describing it as the best on the market.
"Great product!..." Read more
"This is very good quality serum, it’s actually more of a cream...." Read more
"Great product but way overpriced. Can find on many websites for much less" Read more
"I buy this product all the time. The actual product is perfect and does everything it say it will do. My face looks fantastic...." Read more
Customers are very pleased with the results of the serum.
"I love this product and it really works!" Read more
"I love this firming serum. It really works. Unfortunately, it is really expensive, but worth every penny...." Read more
"Works well, but who can afford several hundred a month for face cream?" Read more
"Great product to promote skin rejuvenation and soft silky to apply! Great results" Read more
Customers report positive effects on their skin tone, with reviews mentioning improved appearance, clearer complexion, and enhanced radiance.
"...It’s not magic and doesn’t turn back time, but my skin looks and feels better than it has in years!" Read more
"...not using for a year, just one night and my skin is clearer, more even toned, and less crepey. This is spendy, but it's worth every penny!" Read more
"Great product to promote skin rejuvenation and soft silky to apply! Great results" Read more
"This product is promoted by the skin care company as very beneficial for aging skin. It will take time to see its benefits." Read more
Customers like the texture of the serum, describing it as smooth and silky to apply.
"...a year, just one night and my skin is clearer, more even toned, and less crepey. This is spendy, but it's worth every penny!" Read more
"Great product to promote skin rejuvenation and soft silky to apply! Great results" Read more
"I absolutely love it and combine it with the eye cream . The texture is soo smoth and fast absorbing, It gives the moisture and radiance my skin..." Read more
Customers have mixed opinions about the serum's value for money, with some saying it's worth every penny while others find it pricey.
"...This is spendy, but it's worth every penny!" Read more
"...It really works. Unfortunately, it is really expensive, but worth every penny. I will just have to save my pennies to afford my new bottle." Read more
"...I’ve used it for years and could not be happier. Yes it’s expensive but I use it once a day and easily get at least 3 months." Read more
"...This stuff is well worth the investment!!!" Read more
Reviews with images

Solid choice! Worth the money.
Top reviews from the United States
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- Reviewed in the United States on February 11, 2025Great product! I’m always skeptical about hype when it comes to topical rejuvenating products, and I tried this due to the consistently excellent reviews. My experience has been great! It’s not magic and doesn’t turn back time, but my skin looks and feels better than it has in years!
5.0 out of 5 starsGreat product! I’m always skeptical about hype when it comes to topical rejuvenating products, and I tried this due to the consistently excellent reviews. My experience has been great! It’s not magic and doesn’t turn back time, but my skin looks and feels better than it has in years!Solid choice! Worth the money.
Reviewed in the United States on February 11, 2025
Images in this review
- Reviewed in the United States on October 16, 2023I first started using this serum a few years ago after some laser and microneedling treatments. At the time, my skin had never looked better but I wasn't sure if it was the combination of the product and treatments. I have tried several other growth factor serums since - one of which was even more money than the bio serum, but I keep coming back to this one. None of the other products I have tried even come close to what this does for my 50 year old skin. I swear after not using for a year, just one night and my skin is clearer, more even toned, and less crepey. This is spendy, but it's worth every penny!
- Reviewed in the United States on October 6, 2024I love this product and it really works!
- Reviewed in the United States on July 29, 2020I love this firming serum. It really works. Unfortunately, it is really expensive, but worth every penny. I will just have to save my pennies to afford my new bottle.
- Reviewed in the United States on May 26, 2024Works well, but who can afford several hundred a month for face cream?
- Reviewed in the United States on May 25, 2022You should not be using a dimes worth of this per use. A little goes a long, long way. I’m almost 47 and have nearly zero wrinkles. This isn’t moisturizer it’s an intensive concentrated serum. I’ve used it for years and could not be happier. Yes it’s expensive but I use it once a day and easily get at least 3 months.
- Reviewed in the United States on November 5, 2024This is very good quality serum, it’s actually more of a cream. The problem is it absorbs very quickly into the skin, so one pump is not enough to cover the whole face. You’re lucky if this lasts you a month, it’s more like half a month. It’s too expensive.
- Reviewed in the United States on March 4, 2025Great product but way overpriced. Can find on many websites for much less