
Enjoy fast, free delivery, exclusive deals, and award-winning movies & TV shows with Prime
Try Prime
and start saving today with fast, free delivery
Amazon Prime includes:
Fast, FREE Delivery is available to Prime members. To join, select "Try Amazon Prime and start saving today with Fast, FREE Delivery" below the Add to Cart button.
Amazon Prime members enjoy:- Cardmembers earn 5% Back at Amazon.com with a Prime Credit Card.
- Unlimited Free Two-Day Delivery
- Streaming of thousands of movies and TV shows with limited ads on Prime Video.
- A Kindle book to borrow for free each month - with no due dates
- Listen to over 2 million songs and hundreds of playlists
- Unlimited photo storage with anywhere access
Important: Your credit card will NOT be charged when you start your free trial or if you cancel during the trial period. If you're happy with Amazon Prime, do nothing. At the end of the free trial, your membership will automatically upgrade to a monthly membership.
One-time purchase:
$103.00$103.00 $103.00 per Fl Oz ($103.00$103.00 / Fl Oz)
Ships from: Amazon.com Sold by: Amazon.com
Subscribe & Save:
5%
10%
$97.85$97.85 $97.85 per Fl Oz ($97.85$97.85 / Fl Oz)
$92.70 with 10 percent savings $92.70 $92.70 per Fl Oz ($92.70$92.70 / Fl Oz)
First delivery on Mar 10 FREE delivery Friday, March 7
Ships from: Amazon.com Sold by: Amazon.com
- No fees
- Cancel anytime
Unlock 10% savings
Save 10% when you receive 5 or more products in one auto-delivery to one address. Currently, you'll save 5% on your Jul 4 delivery.Choose how often it's delivered
From once every 2 weeks to once every 6 monthsSkip or cancel any time
We'll send you a reminder before each delivery.Potential Savings
Potential Yearly Savings is an estimate based on your selected delivery frequency and the base discount. Actual savings may change based on delivery frequency and discount eligibility.Pricing
While you will always receive a Subscribe & Save discount, individual product prices can go up or down over time. If the price of your subscribed product changes, the new price will be displayed in your order review email and will be applied only on future shipments. You can review your subscription price and edit or cancel your subscription at any time
Added to cart
-
-
-
-
-
-
-
10 VIDEOS
-

Image Unavailable
Color:
-
-
-
- To view this video download Flash Player
iS CLINICAL Hydra-Cool Serum, Refreshing and Hydrating Skin Face Serum, Anti-Blemish, Anti-Redness
Premium Brand Sourced
We work closely with your favorite premium beauty brands and their approved resellers to ensure the premium products sold in our stores are authentic.
Return this item for free
We offer easy, convenient returns with at least one free return option: no shipping charges. All returns must comply with our returns policy.
Learn more about free returns.- Go to your orders and start the return
- Select your preferred free shipping option
- Drop off and leave!
Learn more
Learn more
Return this item for free
We offer easy, convenient returns with at least one free return option: no shipping charges. All returns must comply with our returns policy.
Learn more about free returns.- Go to your orders and start the return
- Select your preferred free shipping option
- Drop off and leave!
Purchase options and add-ons
Skin Type | Acne Prone, Combination, Normal |
Product Benefits | Provides intensive hydration to help soothe the skin from dehydration, redness, irritation or damage. See more |
Use for | Face |
Scent | Aloe |
Special Ingredients | Antioxidants |
Description
Benefits
Suggested use
Buy it with

Related Climate Pledge Friendly items
- Sustainability features for this product
Sustainability features
This product has sustainability features recognized by trusted certifications.Safer chemicalsMade with chemicals safer for human health and the environment.As certified byOEKO-TEX MADE IN GREEN
Made in Green by Oeko-Tex verifies that the article has been manufactured using processes with a reduced environmental impact and under socially responsible working conditions. The label also verifies that the product has been tested for substances that could harm the body and environment. Thanks to the unique product ID, each product can be easily traced by entering the certification number on the Label Check on the Made in Green website, where more information about the production facilities is provided.Certification NumberM1KN8XW04Worker well-beingManufactured on farms or in facilities that protect the rights and/or health of workers.As certified byOEKO-TEX MADE IN GREEN
Made in Green by Oeko-Tex verifies that the article has been manufactured using processes with a reduced environmental impact and under socially responsible working conditions. The label also verifies that the product has been tested for substances that could harm the body and environment. Thanks to the unique product ID, each product can be easily traced by entering the certification number on the Label Check on the Made in Green website, where more information about the production facilities is provided.Certification NumberM1KN8XW04Manufacturing practicesManufactured using processes that reduce the risk of negative environmental impact.As certified byOEKO-TEX MADE IN GREEN
Made in Green by Oeko-Tex verifies that the article has been manufactured using processes with a reduced environmental impact and under socially responsible working conditions. The label also verifies that the product has been tested for substances that could harm the body and environment. Thanks to the unique product ID, each product can be easily traced by entering the certification number on the Label Check on the Made in Green website, where more information about the production facilities is provided.Certification NumberM1KN8XW04 - Sustainability features for this product
Sustainability features
This product has sustainability features recognized by trusted certifications.Organic contentProduct contains at least 95% organic material.As certified byUSDA Organic
USDA Organic is protected by law, inspected by experts, traced from farm to store, and shaped by public input. USDA develops and enforces the organic standards, which require products to be produced using farming practices that maintain and improve soil and water quality, minimize the use of synthetic materials, conserve biodiversity, and avoid genetic engineering, among other factors. Crops can be certified organic if they’re grown without prohibited substances such as most synthetic fertilizers and pesticides for three years prior to harvest. Livestock are raised on pasture and treated humanely without growth hormones or antibiotics. Organic products do not contain GMOs or artificial colors, flavors, or preservatives. Products that contain a minimum of 95 percent organic ingredients and use the USDA Organic seal are part of Climate Pledge Friendly. - Sustainability features for this product
Sustainability features
This product has sustainability features recognized by trusted certifications.Safer chemicalsMade with chemicals safer for human health and the environment.As certified byCradle to Cradle Certified
Cradle to Cradle Certified is the world's most comprehensive standard for safe, circular and responsible products. Certified products meet science-based requirements that have positive benefits including health and wellbeing, material reuse, emissions reductions, water quality, and fair and safe labor practices. The Cradle to Cradle Certified Product Standard is set by the Cradle to Cradle Products Innovation Institute, a global non-profit dedicated to powering innovation for a prosperous economy.Certification LevelSILVER ACHIEVEMENT LEVELManufacturing practicesManufactured using processes that reduce the risk of negative environmental impact.As certified byCradle to Cradle Certified
Cradle to Cradle Certified is the world's most comprehensive standard for safe, circular and responsible products. Certified products meet science-based requirements that have positive benefits including health and wellbeing, material reuse, emissions reductions, water quality, and fair and safe labor practices. The Cradle to Cradle Certified Product Standard is set by the Cradle to Cradle Products Innovation Institute, a global non-profit dedicated to powering innovation for a prosperous economy.Certification LevelSILVER ACHIEVEMENT LEVELWorker well-beingManufactured on farms or in facilities that protect the rights and/or health of workers.As certified byCradle to Cradle Certified
Cradle to Cradle Certified is the world's most comprehensive standard for safe, circular and responsible products. Certified products meet science-based requirements that have positive benefits including health and wellbeing, material reuse, emissions reductions, water quality, and fair and safe labor practices. The Cradle to Cradle Certified Product Standard is set by the Cradle to Cradle Products Innovation Institute, a global non-profit dedicated to powering innovation for a prosperous economy.Certification LevelSILVER ACHIEVEMENT LEVEL - Sustainability features for this product
Sustainability features
This product has sustainability features recognized by trusted certifications.Packaging efficiencyReduced air and/or water in the product or packaging for more efficient transportation.As certified byCompact by Design (Amazon-developed Certification)
Compact by Design identifies products that, while they may not always look very different, have a more efficient design. By reducing water and/or air in the product or packaging, these become more efficient to ship. At scale, these small differences in product size and weight lead to significant carbon emission reductions. - Sustainability features for this product
Sustainability features
This product has sustainability features recognized by trusted certifications.Safer chemicalsMade with chemicals safer for human health and the environment.As certified byCradle to Cradle Certified
Cradle to Cradle Certified is the world's most comprehensive standard for safe, circular and responsible products. Certified products meet science-based requirements that have positive benefits including health and wellbeing, material reuse, emissions reductions, water quality, and fair and safe labor practices. The Cradle to Cradle Certified Product Standard is set by the Cradle to Cradle Products Innovation Institute, a global non-profit dedicated to powering innovation for a prosperous economy.Certification LevelSILVER ACHIEVEMENT LEVELManufacturing practicesManufactured using processes that reduce the risk of negative environmental impact.As certified byCradle to Cradle Certified
Cradle to Cradle Certified is the world's most comprehensive standard for safe, circular and responsible products. Certified products meet science-based requirements that have positive benefits including health and wellbeing, material reuse, emissions reductions, water quality, and fair and safe labor practices. The Cradle to Cradle Certified Product Standard is set by the Cradle to Cradle Products Innovation Institute, a global non-profit dedicated to powering innovation for a prosperous economy.Certification LevelSILVER ACHIEVEMENT LEVELWorker well-beingManufactured on farms or in facilities that protect the rights and/or health of workers.As certified byCradle to Cradle Certified
Cradle to Cradle Certified is the world's most comprehensive standard for safe, circular and responsible products. Certified products meet science-based requirements that have positive benefits including health and wellbeing, material reuse, emissions reductions, water quality, and fair and safe labor practices. The Cradle to Cradle Certified Product Standard is set by the Cradle to Cradle Products Innovation Institute, a global non-profit dedicated to powering innovation for a prosperous economy.Certification LevelSILVER ACHIEVEMENT LEVEL - Sustainability features for this product
Sustainability features
This product has sustainability features recognized by trusted certifications.Forestry practicesMade with materials harvested from responsibly managed forests.As certified byRainforest Alliance
Rainforest Alliance is an international non-profit organization working to create a better future for people and nature. By choosing Rainforest Alliance certified products, you help support farmers to follow more sustainable, climate-smart farming practices that protect natural resources and the environment by using land, water, and energy more carefully. These practices also safeguard carbon-storing forests and help farmers mitigate and adapt to climate change, which ultimately improves their livelihoods.The Forest Stewardship Council
The Forest Stewardship Council (FSC) supports responsible forestry, which is a vital solution to combat climate change. Choosing FSC-certified products – whether furniture, building materials, paper, rubber, or textiles – helps protect forests, wildlife, clean water and supports the Indigenous Peoples, forest workers and communities who depend on them. Choosing FSC-certified products can also help to mitigate climate change by supporting responsible management of the world’s forests. For a better future, choose FSC.Worker well-beingManufactured on farms or in facilities that protect the rights and/or health of workers.As certified byRainforest Alliance
Rainforest Alliance is an international non-profit organization working to create a better future for people and nature. By choosing Rainforest Alliance certified products, you help support farmers to follow more sustainable, climate-smart farming practices that protect natural resources and the environment by using land, water, and energy more carefully. These practices also safeguard carbon-storing forests and help farmers mitigate and adapt to climate change, which ultimately improves their livelihoods.Farming practicesMade with materials harvested from responsibly managed farms.As certified byRainforest Alliance
Rainforest Alliance is an international non-profit organization working to create a better future for people and nature. By choosing Rainforest Alliance certified products, you help support farmers to follow more sustainable, climate-smart farming practices that protect natural resources and the environment by using land, water, and energy more carefully. These practices also safeguard carbon-storing forests and help farmers mitigate and adapt to climate change, which ultimately improves their livelihoods.BiodiversityMade with materials harvested in a way that helps protect animals, plants, and a healthy ecosystem.As certified byRainforest Alliance
Rainforest Alliance is an international non-profit organization working to create a better future for people and nature. By choosing Rainforest Alliance certified products, you help support farmers to follow more sustainable, climate-smart farming practices that protect natural resources and the environment by using land, water, and energy more carefully. These practices also safeguard carbon-storing forests and help farmers mitigate and adapt to climate change, which ultimately improves their livelihoods.
From the manufacturer

Explore More You Might Like
![]() Hydra-Cool Serum | ![]() Active Serum | ![]() Youth Eye Complex | ![]() Cleansing Complex | |
---|---|---|---|---|
Customer Reviews
|
4.6 out of 5 stars 424
|
4.6 out of 5 stars 808
|
4.3 out of 5 stars 363
|
4.5 out of 5 stars 2,509
|
Price
| $103.00$103.00 | $148.00$148.00 | $120.00$120.00 | $49.00$49.00 |
Step in Regimen
| 3. Hydrate | 2. Treat | 2. Treat | 1. Cleanse |
Benefits
| Hydrating, Calming, Soothing | Clearing + Anti-Aging | Hydrate + Wrinkle Reduction | Clearing + Deep-Cleansing |
Key Ingredients
| Hyaluronic Acid, Vitamin B5 | AHA + BHA, Arbutin Extract | Acetyl Octapeptide-3,Vitamin A | AHA + BHA, Centella Asiatica |
Texture
| Lightweight Serum | Lightweight Serum | Medium-weight Cream | Lightweight Clear Gel |
Skin Type
| All Skin Types | Normal, dry, oily, combination | Aging Skin around eyes | All Skin Types |
Product details
- Is Discontinued By Manufacturer : No
- Product Dimensions : 2.88 x 1.63 x 4.4 inches; 1.6 ounces
- Item model number : 1005
- UPC : 817244010074 012353814401 000000047173 710069461697 123538144012
- Manufacturer : iS CLINICAL
- ASIN : B000IOLCWI
- Country of Origin : USA
- Best Sellers Rank: #27,238 in Beauty & Personal Care (See Top 100 in Beauty & Personal Care)
- #602 in Facial Serums
- Customer Reviews:
Videos
Videos for this product
1:45
Click to play video
Is The IS CLINICAL HYDRA COOL SERUM Worth The Buy?!
Marina’s Mail
Videos for this product
1:09
Click to play video
Sensitive, Dry Skin? My Reaction To Using This
The Nomad Nextdoor
Videos for this product
3:18
Click to play video
Innovative Skincare - Acne
Amazon Luxury Beauty
Videos for this product
1:39
Click to play video
IS Clinical Hydra Cool Serum (mild, gentle)- How to use it?
Kigaa
Videos for this product
1:59
Click to play video
Review of the IS Clinical Hydra-Cool Serum
Curly Rina
Videos for this product
2:04
Click to play video
Check out my 2 cool recent buys| serum & towelletes!
Kigaa
Videos for this product
0:40
Click to play video
Revitalize Your Skin After 50 With iS Clinical Serum
Happening Hounds
Videos for this product
0:48
Click to play video
Product Overview Video
Amazon Product Imaging
Looking for specific info?
Customer reviews
Customer Reviews, including Product Star Ratings help customers to learn more about the product and decide whether it is the right product for them.
To calculate the overall star rating and percentage breakdown by star, we don’t use a simple average. Instead, our system considers things like how recent a review is and if the reviewer bought the item on Amazon. It also analyzed reviews to verify trustworthiness.
Learn more how customers reviews work on AmazonCustomers say
Customers appreciate the skin serum for its soothing and hydrating properties. They find it refreshing and effective at replenishing moisture to their dehydrated skin. The cooling sensation is also appreciated, especially in cold weather. While most customers are satisfied with the product's functionality, absorbency, and appearance, some have mixed opinions on skin sensitivity.
AI-generated from the text of customer reviews
Customers appreciate the skin serum. They find it refreshing, soothing, and a perfect moisturizer that leaves their skin soft and smooth. The serum helps reduce breakouts and improve skin clarity. It's gentle on acne-prone skin and doesn't cause breakouts.
"...and had good success with it, but this particular one, has worked wonders on my skin!! The hyaluronic serum is excellent, I recommend this product!" Read more
"...peels and laser treatments and used this after and it never irritates my skin. I fly a lot and this adds moisture back into my dehydrated skin...." Read more
"I love this serum. It’s very soothing on the skin and doesn’t leave you feeling oily...." Read more
"B/c it's pricey. But it has healed and revitalized my extra dry, sensitive skin like no other product has before...." Read more
Customers like the quality of the serum. They say it keeps their skin hydrated throughout the day. Some find it too expensive, while others consider it a great everyday product at a better price.
"Good items" Read more
"I have used this product for a few years. The product is fine, overpriced given how long it lasts, and a disaster when it comes to delivery method...." Read more
"Good quality. But too expensive" Read more
"I like it, good product" Read more
Customers appreciate the serum's hydrating properties. They say it adds moisture back to their dehydrated skin and leaves it feeling hydrated. Some reviewers mention it heals and revitalizes extra dry, sensitive skin like no other product.
"...In addition, this is hydrating enough for me to use as a moisturizer in the summer...." Read more
"B/c it's pricey. But it has healed and revitalized my extra dry, sensitive skin like no other product has before...." Read more
"...And it’s nice in that it does add a good amount of moisture. There are two cons in my opinion. What they ship has a dropper, Not the pump..." Read more
"...Hydra-cool doesn't break me out and helps add more moisture after cleansing...." Read more
Customers appreciate the cooling sensation of the skin serum. They find it helpful in cold weather and say it doesn't break them out. The serum helps add moisture after cleansing and is great for acne-prone skin.
"Very helpful for very cold weather." Read more
"...Hydra-cool doesn't break me out and helps add more moisture after cleansing...." Read more
"...Exceptional skincare. This particular product is my fav, nice cooling sensation and my skin loves." Read more
"...Love it. It's definitely cooling, makes the skin feel very refreshed. Didn't irritate my incredibly sensitive skin...." Read more
Customers like the serum's functionality. They say it works well with the Hydra-Cool mask and is great after sun.
"It simply works perfect!" Read more
"Works perfect with Hydra-Cool mask ! And great after sun!" Read more
"...Cool heaing. Works fantastic." Read more
"It does the job I bought i for." Read more
Customers like the serum's absorbency. They say it soaks in quickly and provides immediate results.
"...It soaks in quickly (does not leave a blue tint on skin despite the color of the serum) and always leaves my skin feeling hydrated...." Read more
"I love it you see instant results" Read more
"...Hydra cool serum is clear and feels cool and quickly absorbs into the skin. Not happy. I wouldn't buy from this seller again." Read more
Customers like the appearance of the serum. They say it makes their face look and feel amazing.
"...IS Clinical is an beautiful product, also with awesome customer care!" Read more
"When mixed with the pro super serum my face feels and looks amazing. I recommend this to anybody." Read more
"I love this product; it makes your skin so smooth and healthy-looking. And I think that this vendor is perhaps the best I've dealt with on Amazon...." Read more
Customers have different experiences with the skin serum. Some find it doesn't irritate their sensitive skin, leaving their face smooth and soft. Others say it can cause irritation or clog pores.
".../sensitive/sometimes breakout prone skin and this does not irritate or break out my skin in any way...." Read more
"...It can feel nice, but if your skin is sensitive, it can also cause irritation. The product would be better without the menthol...." Read more
"...now. It made a huge difference in the clarity and firmness of my skin...." Read more
"...Didn't irritate my incredibly sensitive skin. I can imagine it will be the best in the summer...." Read more
Reviews with images

Top reviews from the United States
There was a problem filtering reviews right now. Please try again later.
- Reviewed in the United States on January 1, 2025Size: 1 Fl Oz (Pack of 1)Verified PurchaseI've used this brand before and had good success with it, but this particular one, has worked wonders on my skin!! The hyaluronic serum is excellent, I recommend this product!
- Reviewed in the United States on January 24, 2025Size: 0.5 Fl Oz (Pack of 1)Verified PurchaseVery helpful for very cold weather.
- Reviewed in the United States on February 11, 2025Size: 0.5 Fl Oz (Pack of 1)Verified PurchaseGood items
5.0 out of 5 starsGood itemsFast
Reviewed in the United States on February 11, 2025
Images in this review
- Reviewed in the United States on March 29, 2018Size: 1 Fl Oz (Pack of 1)Verified PurchaseI’ve tried quite a few other hyaluronic acid type serums for hydration from other brands and this is my favorite.
I have combination/sensitive/sometimes breakout prone skin and this does not irritate or break out my skin in any way. It soaks in quickly (does not leave a blue tint on skin despite the color of the serum) and always leaves my skin feeling hydrated. The feel of this serum is more slippery/silky as opposed to sticky like some serums. I have gotten chemical peels and laser treatments and used this after and it never irritates my skin. I fly a lot and this adds moisture back into my dehydrated skin. In addition, this is hydrating enough for me to use as a moisturizer in the summer.
I have tried a couple other brands since I started using this and always come back to this one. I haven’t found anything I like as much. Love all the iS Clinical products I’ve tried. Great for people with sensitive or breakout prone skin.
- Reviewed in the United States on September 3, 2023Size: 1 Fl Oz (Pack of 1)Verified PurchaseI love this serum. It’s very soothing on the skin and doesn’t leave you feeling oily. I suffer from combination skin, and this product has helped tremendously.
- Reviewed in the United States on August 25, 2020Size: 1 Fl Oz (Pack of 1)Verified PurchaseB/c it's pricey. But it has healed and revitalized my extra dry, sensitive skin like no other product has before. I had to wait a while before buying more when I ran out and my face skin rapidly deteriorated. This is now a must have.
- Reviewed in the United States on October 11, 2023Size: 0.5 Fl Oz (Pack of 1)Verified PurchaseI couldn’t get this product because it was damaged in shipment, but I’ve used it before. And it’s nice in that it does add a good amount of moisture. There are two cons in my opinion.
What they ship has a dropper, Not the pump
Shown. This contains menthol. It can feel nice, but if your skin is sensitive, it can also cause irritation. The product would be better without the menthol. This is also pricey, and I think they’re are more affordable and equally effective options. Does result in nice added moisture though.
- Reviewed in the United States on May 8, 2023Size: 1 Fl Oz (Pack of 1)Verified PurchaseIt simply works perfect!
Top reviews from other countries
- DhanushaReviewed in Canada on November 27, 2024
5.0 out of 5 stars Must try for sensitive skin
Size: 1 Fl Oz (Pack of 1)Verified PurchaseI’ve been using this serum for a couple of years now, and it’s become an essential part of my skincare routine. My skin is extremely sensitive and reactive, but this serum works like a charm without causing any irritation. It leaves my skin feeling incredibly soft, hydrated, and noticeably shiny with a healthy glow. Since I started using it, I haven’t looked for another product—it’s that good! If you’re dealing with dull or dehydrated skin, this is a must-try.
-
antje blankeReviewed in Germany on June 12, 2021
5.0 out of 5 stars Absolut hilfreiches Produkt.
Size: 1 Fl Oz (Pack of 1)Verified PurchaseBeruhigt die Haut. Sehr hilfreich.
-
AntonhReviewed in Mexico on April 19, 2019
5.0 out of 5 stars En general todo bien
Size: 0.5 Fl Oz (Pack of 1)Verified PurchaseEs un buen producto, tardo mucho en llegar
-
Marta MonellReviewed in Spain on April 14, 2019
5.0 out of 5 stars Buena compra
Size: 1 Fl Oz (Pack of 1)Verified PurchasePerfecto, tal i como se anunciaba
- Louise ElmsReviewed in Australia on June 15, 2019
5.0 out of 5 stars Cooling and hydrating
Size: 1 Fl Oz (Pack of 1)Verified PurchaseLove this product